14 Aug Testosterone does not cause lower urinary tract symptoms
Testosterone replacement therapy is an essential component of a comprehensive strategy aimed at slowing, stopping and in some cases reversing biomarkers of ageing in men.
Loss of lean muscle mass, increase in abdominal fat, worsening of metabolic syndrome, increase in irritable mood, and lack of vitality are biomarkers of aging that are often ignored when focusing on the sexual aspects of testosterone replacement therapy in men.
These factors however, account for the increase in risk of death, cardiovascular disease and cancer, including prostate cancer in men with low or even low normal testosterone balance. Although there are many concerns raised about replacing testosterone to optimal physiological levels in men, controversy surrounding real and unsubstantiated side effects abound, not the least of which erroneously states that testosterone replacement therapy increases symptoms and signs of prostate enlargement.
TRT may improve components of the metabolic syndrome, which is associated with worsening LUTS. Furthermore, the evidence suggests that TRT may decrease prostatic inflammation, which is also associated with worsening LUTS. The data on the relationship between TRT and LUTS have never shown worsening of LUTS, often show no change in LUTS, and occasionally show improvement.